“People” and “Land” health — contributing by fostering human resources capable not only of basic research but of conducting translational research bridging toward clinical application, and developing multiperspective experts who understand the collaboration of medicine, pharmacy, and nursing to lead global medical science and healthcare Educational features of the Medical Life Sciences Program are as follows: Comprehensive education from both basic and clinical perspectives regarding disease causes, treatment, and prevention Training to develop the capacity to carry out translational research that bridges to clinical application Instruction in both Oriental and Western medicine approaches to address medical challenges Teaching to grasp cooperation among medicine, pharmacy, and nursing and to address medical issues from a multiperspective stance Degrees Available Course Major Program Degree Awarded Doctoral course Integrated Medicine & Pharmaceutical Sciences Medical Life Sciences Program Doctor of Medicine Research Themes Research Theme Pickup Towards Understanding the Pathophysiology of Mental DisordersTo understand the pathophysiology of mental disorders such as schizophrenia, we conduct advanced clinical research using biological indicators (biomarkers) including brain imaging and electroencephalography (EEG). Lung Organ EngineeringWithin a bioreactor, we fabricate bio-engineered lung using decellularized scaffolds. Creating organs is a dream for humanity; through networks with the engineering and pharmacy departments, and many institutions domestically and internationally, we walk step by step toward that goal. Research to reduce pregnancy-induced hypertension leading to maternal deathWhile childbirth is one of life’s most joyful events, hypertensive disorders of pregnancy can be a cause of maternal or fetal death. Our laboratory not only develops treatments for known etiologies but also identifies novel causative factors, aiming through this research to contribute to maternal and child health. Oral Science Contributing to Extension of Healthy LifespanThe oral cavity hosts resident microbiota and performs diverse functions—mastication, swallowing, speech, aesthetic functions—and has broad connections with systemic health. We analyze how oral bacteria or function influence systemic conditions through disease and therapy to help extend healthy lifespan. From Epidemiology to Health PolicyThe Department of Epidemiology and Health Policy conducts epidemiological studies, identifies population health problems, clarifies their underlying factors, and proposes health policies. For example, we have recently found that workplace stress and work–life balance are associated with declines in labor productivity, increased Internet addiction, and the onset of depression. We also conduct international collaborative research with University College London and the University of Helsinki. By elucidating the social determinants of health within the context of Japanese culture and contemporary society, we contribute to addressing today’s population health challenges. Toward Improving the Effectiveness of Cancer Genomic MedicineCancer genomic medicine, which comprehensively detects genomic alterations in cancer and links them to appropriate therapies, is considered a central component of next-generation cancer care. However, despite its promise, cancer genomic medicine currently faces several challenges, including a low rate of access to matched therapies. In this course, we aim to elucidate the real-world status of cancer genomic medicine through the analysis of data derived from routine clinical practice, and to explore strategies to improve its clinical effectiveness. Microbial Evolution and Pathophysiology: Cutting-edge Insights for Clinical ImpactWhy do microbes evolve while altering their interactions with humans? While tracking the ongoing threats of antimicrobial resistance and high pathogenicity, our research focuses on providing the most up-to-date insights into pathophysiology—delivering a direct and clinically significant impact on diagnosis, treatment, and disease control. Neural Circuitry for Communication Sound PerceptionFor humans and animals, proper perception of communication sounds is vitally important. Using animal models, we clarify how communication sounds are distinguished from other sounds in the brain, elucidating neural circuits as well as correlating structure, function, and behavior. Towards Understanding the Pathophysiology of Mental DisordersTo understand the pathophysiology of mental disorders such as schizophrenia, we conduct advanced clinical research using biological indicators (biomarkers) including brain imaging and electroencephalography (EEG). Lung Organ EngineeringWithin a bioreactor, we fabricate bio-engineered lung using decellularized scaffolds. Creating organs is a dream for humanity; through networks with the engineering and pharmacy departments, and many institutions domestically and internationally, we walk step by step toward that goal. Research to reduce pregnancy-induced hypertension leading to maternal deathWhile childbirth is one of life’s most joyful events, hypertensive disorders of pregnancy can be a cause of maternal or fetal death. Our laboratory not only develops treatments for known etiologies but also identifies novel causative factors, aiming through this research to contribute to maternal and child health. Oral Science Contributing to Extension of Healthy LifespanThe oral cavity hosts resident microbiota and performs diverse functions—mastication, swallowing, speech, aesthetic functions—and has broad connections with systemic health. We analyze how oral bacteria or function influence systemic conditions through disease and therapy to help extend healthy lifespan. From Epidemiology to Health PolicyThe Department of Epidemiology and Health Policy conducts epidemiological studies, identifies population health problems, clarifies their underlying factors, and proposes health policies. For example, we have recently found that workplace stress and work–life balance are associated with declines in labor productivity, increased Internet addiction, and the onset of depression. We also conduct international collaborative research with University College London and the University of Helsinki. By elucidating the social determinants of health within the context of Japanese culture and contemporary society, we contribute to addressing today’s population health challenges. Toward Improving the Effectiveness of Cancer Genomic MedicineCancer genomic medicine, which comprehensively detects genomic alterations in cancer and links them to appropriate therapies, is considered a central component of next-generation cancer care. However, despite its promise, cancer genomic medicine currently faces several challenges, including a low rate of access to matched therapies. In this course, we aim to elucidate the real-world status of cancer genomic medicine through the analysis of data derived from routine clinical practice, and to explore strategies to improve its clinical effectiveness. Microbial Evolution and Pathophysiology: Cutting-edge Insights for Clinical ImpactWhy do microbes evolve while altering their interactions with humans? While tracking the ongoing threats of antimicrobial resistance and high pathogenicity, our research focuses on providing the most up-to-date insights into pathophysiology—delivering a direct and clinically significant impact on diagnosis, treatment, and disease control. Neural Circuitry for Communication Sound PerceptionFor humans and animals, proper perception of communication sounds is vitally important. Using animal models, we clarify how communication sounds are distinguished from other sounds in the brain, elucidating neural circuits as well as correlating structure, function, and behavior. Educational Goals・Educational Objectives・Three Policies Educational Objectives The Graduate School of this university aims to teach and research both the theory and application of scholarship, explore them in depth, and cultivate profound academic knowledge and exceptional ability needed to assume professions requiring high specialization, thereby contributing to cultural advancement. Educational Goals The Medical Sciences Program seeks to teach broad knowledge including clinical pharmacy, and cultivate medical literacy to deeply understand disease and empathize with patients. Based on human dignity and high ethics, the program aims to develop creativity, judgment, problem-solving capability, and communication. Graduates will be educators, researchers, advanced professionals, and specialists who can lead in the domain of clinical medicine. Diploma Policy Policy on Completion Certification and Degree Conferment Those who satisfy the completion requirements will be awarded the degree of Doctor of Medicine (医学博士). The policy rests on achieving competencies in the domains of foundational ability, specialized knowledge, ethics, and creativity, as well as ability in translational research and understanding across medical disciplines. Achievement Goals and Performance Indicators Fundamental Ability Achievement Goals: Ability to collect specialized information, identify problems, think logically, communicate research content, read and interpret English scientific literature, and engage in specialist discussion. Performance Indicators: Completion of elective and required courses in the broad domain, and ability to discuss research topics and literature content. Specialized Knowledge Achievement Goals: As an independent researcher, identify research problems in specialized fields and propose solutions, and present results in academic forums. Performance Indicators: Ability to engage in research and publish or present outcomes, and proficiency in domain-level discussion. Sense of Ethics Achievement Goals: Understand research misconduct, and maintain high normative awareness toward research ethics. Performance Indicators: Completion of graduate common course “Research Ethics” and departmental common course “Medical & Pharmaceutical Professional Research Theory,” and required ethics training (clinical research, recombinant DNA, animal experiments, radiation use, etc.). Creativity Achievement Goals: Ability to generate new knowledge and derive further value, set next research problems, and communicate outcomes. Performance Indicators: Presentation in “Interdisciplinary Presentation Seminar I & II,” author original manuscripts, publish in peer-reviewed journals, present at conferences, and pass doctoral thesis examination and defense. Translational Research Ability & Medical Knowledge Achievement Goals: Possess knowledge and skills to elucidate disease mechanisms, develop diagnostics or therapies, conduct preventive or therapeutic research, and translate basic findings into clinical application. Performance Indicators: Execution of translational research projects, integration of medical science knowledge into research, and successful defense of a clinically oriented doctoral dissertation. Curriculum Policy Curriculum Design Through individual guidance in the student’s research laboratory, students acquire foundational specialized knowledge and techniques in medical research. The doctoral thesis must include novelty, academic significance, and clinical translational potential. To ensure acquisition of broad foundational ability, advanced specialty knowledge, ethics, and translational research capability, the curriculum includes diverse elective courses, special seminars taught by external lecturers, training in research ethics, and required courses in methodology. Implementation Policy Student-led active learning centered in their research laboratory is emphasized. In years 1–3, students take a broad range of lecture and practicum courses to build foundational ability, specialized knowledge, and ethics. In year 4, they focus on writing and presenting the doctoral thesis. Learning Content, Learning Methods, and Evaluation of Learning Outcomes Fundamental Ability Fundamental Ability Learning Content: Specialized knowledge, problem identification, reading/interpreting English articles, and presentation of research content. Learning Methods: Active learning via information gathering, planning research, reading relevant literature, and discussion. Evaluation of Learning Outcomes: Evaluated via exams, reports, presentations, and assessment of doctoral thesis and oral defense per established criteria. Specialized Knowledge Learning Content: Conduct research in the specialized domain, collect knowledge, design experiments or investigations. Learning Methods: Enrollment in program-specific courses, lab work, presentation and discussion of research outcomes in academic settings. Evaluation of Learning Outcomes: Evaluation of thesis content and oral defense per criteria. Sense of Ethics Learning Content: Training in research ethics, respect for persons, and compliance with legal and procedural norms. Learning Methods: Courses “Research Ethics” and “Medical & Pharmaceutical Professional Research Theory,” lectures and lab guidance in legal procedures. Evaluation of Learning Outcomes: Exams and reports in ethics courses; compliance and ethical integrity evaluated in thesis criteria. Creativity Learning Content: Proposal, execution, and dissemination of new research, preparation for presentation and publication. Learning Methods: Seminars “Interdisciplinary Presentation I & II,” active learning in writing research papers, preparing for conferences, and presenting outcomes. Evaluation of Learning Outcomes: Presentation and Q&A performance, and evaluation of doctoral thesis and defense. Admissions Policy Policy on Student Admissions We seek individuals who aspire to engage in cutting-edge research in medicine and healthcare. Applicants should have enthusiasm and capability for medical/healthcare research and the aspiration to contribute to global medicine. We prefer those with high basic academic ability across diverse disciplines who aim to pursue advanced research in medical science. Fundamental Policy for Student Selection (Types of Entrance Examinations and Evaluation Methods) To admit diverse students including foreign ones, both April and October entry are allowed, and two admissions are held annually. General Entrance Examination Selection via foreign language examination (external English tests), oral interview, and academic transcript evaluation. The candidates’ ability, motivation, and competence equivalent to a 6-year medical school graduate are assessed. Special Entrance Examination for International Students Uses the same evaluation components: English exam, oral exam, transcript review. Expected Attributes and Abilities Fundamental Ability Candidates should have intellectual interest in research fields, practice proactive learning, basic English reading skills for scientific literature, and ability to engage in logical discussion. Specialized Knowledge Candidates should be able to learn actively, engage in discussion of related knowledge and literature, and gather specialized knowledge independently. Sense of Ethics Candidates must possess normative awareness of research ethics and aspire to high professional ethics in medical and life science fields. Creativity Broad intellectual curiosity and ability to set new research problems and explore solutions based on research outcomes are highly valued. Curriculum & Course Models Curriculum Map Course Models Research Theme: Multidimensional Human Resources Capable of Leading Global Medicine and Healthcare with an Understanding of Collaboration in Medicine, Pharmacy, and Nursing Specific human resources to be trained: Research on elucidating the pathophysiology of heart failure and its clinical applications, especially non-pharmacological treatments for severe heart failure and mechanical circulatory support. Graduate School Common Subjects Department Common Subjects Program Specialized Subjects Specialized Subjects Special Research 1st Year 1T Research Ethics 1 Advanced Cooperative Research Lecture on Medical and Pharmaceutical Sciences 1 Advanced Health Care System and Management 1 Advanced Cardiology and Nephrology 2 Advanced Cardiothoracic Surgery 2 Advanced Lecture on Medical Sciences 6 Advanced Training in Medical Sciences 2 Advanced Lecture on State-of-the-Art Medical Sciences 1 Advanced Research in Medical Sciences 10 2T 3T Interdisciplinary Presentation Exercises Ⅰ 1 Science, Technology and Sustainable Society 1 Advanced Cooperative Lecture on Medical and Nursing Sciences 1 4T 2nd Year 1T 2T 3T Interdisciplinary Presentation Exercises Ⅱ 1 4T 3rd Year 1T 2T 3T 4T 4th Year 1T 2T 3T 4T Credits Earned 4 2 14 10 Total Credits Earned: 30 Research Theme: Human Resources Capable of Conducting Translational Research Bridging Basic Research and Clinical Application Specific human resources to be trained: Elucidating the mechanism of the DOHaD hypothesis via NAD metabolism and developing early intervention methods. Graduate School Common Subjects Department Common Subjects Program Specialized Subjects Specialized Subjects Special Research 1st Year 1T Research Ethics 1 Advanced Cooperative Research Lecture on Medical and Pharmaceutical Sciences 1 Advanced Health Care System and Management 1 Advanced Molecular and Medical Pharmacology 2 Advanced Pediatric Developmental Medicine 2 Advanced Lecture on Medical Sciences 6 Advanced Training in Medical Sciences 2 Advanced Lecture on State-of-the-Art Medical Sciences 1 Advanced Research in Medical Sciences 10 2T 3T Interdisciplinary Presentation Exercises Ⅰ 1 Science, Technology and Sustainable Society 1 Advanced Cooperative Lecture on Medical and Nursing Sciences 1 4T 2nd Year 1T 2T 3T Interdisciplinary Presentation Exercises Ⅱ 1 4T 3rd Year 1T 2T 3T 4T 4th Year 1T 2T 3T 4T Credits Earned 4 2 14 10 Total Credits Earned: 30 Faculty Members Research field Name Link Anatomy and Neuroscience ProfessorIchijo Hiroyuki Pure Anatomy and Neuroscience Asoociate ProfessorNakamura Tomoya Pure Anatomy and Neuroscience Assistant ProfessorKusui Yuka Pure Integrative Neuroscience Associate ProfessorNoritake Atsushi Pure Molecular Brain Science ProfessorInokuchi Kaoru Pure Molecular Brain Science Associate ProfessorNomoto Masanori Pure Systems Function and Morphology ProfessorIto Tetsufumi Pure Diagnostic Pathology ProfessorHirabayashi Kenichi Pure Molecular Neuropathology ProfessorTakata Katsuyoshi Pure Molecular Neuropathology Associate ProfessorYamamoto Seiji Pure Molecular Neuroscience Associate ProfessorYoshida Tomoyuki Pure Molecular Immunology ProfessorKobayashi Eiji Pure Molecular Immunology Associate ProfessorShitaoka Kiyomi Pure Molecular Immunology Assistant ProfessorKurosawa Mie Pure Microbiology ProfessorMorinaga Yoshitomo Pure Microbiology Assistant ProfessorYamada Hiroshi Pure Microbiology Assistant ProfessorRudy Hermawan Pure Molecular and Medical Pharmacology ProfessorNakagawa Takashi Pure Molecular and Medical Pharmacology LecturerYaku Keisuke Pure Epidemiology & Health Policy ProfessorSekine Michikazu Pure Epidemiology & Health Policy Associate ProfessorYamada Masaaki Pure Epidemiology & Health Policy Assistant ProfessorTatsuse Takashi Pure Legal Medicine ProfessorNishida Naoki Pure Legal Medicine Associate ProfessorHata Yukiko Pure Health Professional Education ProfessorTakamura Akiteru Pure System Emotional Science ProfessorNishimaru Hiroshi Pure System Emotional Science Assistant professorSetogawa Tsuyoshi Pure System Emotional Science Associate ProfessorMatsumoto Jumpei Pure Clinical and Cognitive Neuroscience ProfessorHakamata yuko Pure Gene Expression and Regulation Associate ProfessorKaida Daisuke Pure Diabetes and metabolism, rheumatic and respiratory diseases ProfessorKato Masaru Pure Diabetes and metabolism, rheumatic and respiratory diseases Associate ProfessorFujisaka Shiho Pure Cardiology and Nephrology ProfessorKinugawa Koichiro Pure Gastroenterology ProfessorYasuda Ichiro Pure Gastroenterology Associate ProfessorTajiri Kazuto Pure Gastroenterology Assistant ProfessorShimada Seitaro Pure Inflammatory Bowel Disease ProfessorWatanabe Kenji Pure Clinical Infectious Diseases ProfessorYamamoto Yoshihiro Pure Clinical Infectious Diseases Associate ProfessorNagaoka Kentaro Pure Clinical Infectious Diseases LecturerKawasuji Hitoshi Pure Dermatology Associate ProfessorMakino Teruhiko Pure Pediatric Developmental Medicine ProfessorImai Chihaya Pure Neonatology ProfessorYoshida Taketoshi Pure Neuropsychiatry ProfessorTakahashi Tsutomu Pure Neuropsychiatry Associate ProfessorHiguchi Yuko Pure Neuropsychiatry LecturerSasabayashi Daiki Pure Neuropsychiatry Assistant ProfessorKobayashi Haruko Pure Diagnostic and Therapeutic Radiology Associate ProfessorKido Aki Pure Radiation Oncology ProfessorSaitoh Jun-ichi Pure Cardiothoracic Surgery ProfessorYoshimura Naoki Pure Cardiothoracic Surgery ProfessorTsuchiya Tomoshi Pure Cardiothoracic Surgery Assistant ProfessorToritsuka Daisuke Pure Department of Surgery & Science ProfessorFujii Tsutomu Pure Department of Surgery & Science ProfessorOkumura Tomoyuki Pure Orthopaedics and Locomotor System Science ProfessorKawaguchi Yoshiharu Pure Orthopaedics and Locomotor System Science Associate ProfessorYahara Yasuhito Pure Orthopaedics and Locomotor System Science Assistant ProfessorZukawa Mineyuki Pure Obstetrics and Gynecology ProfessorNakashima Akitoshi Pure Obstetrics and Gynecology Associate ProfessorYoneda Satoshi Pure Obstetrics and Gynecology LecturerShima Tomoko Pure Ophthalmology ProfessorHayashi Atsushi Pure Ophthalmology LecturerYunoki Tatsuya Pure Ophthalmology LecturerMihara Miharu Pure Otorhinolaryngology-Head and Neck Surgery ProfessorMorita Yuka Pure Urology ProfessorKitamura Hiroshi Pure Urology Associate ProfessorNishiyama Naotaka Pure Anesthesiology and Management During Perioperative Period ProfessorTakazawa Tomonori Pure Anesthesiology and Management During Perioperative Period Assistant ProfessorOnishi Kenta Pure Comprehensive Oral Sciences ProfessorYamada Shinichi Pure Comprehensive Oral Sciences LecturerMiura Keiichiro Pure Clinical Laboratory and Molecular Pathology ProfessorNiimi Hideki Pure Japanese Oriental Medicine ProfessorKainuma Mosaburo Pure Japanese Oriental Medicine Associate ProfessorFujimoto Makoto Pure Emergency Medicine ProfessorDoi Tomoaki Pure Emergency Medicine Assistant ProfessorKusuzawa Keigo Pure Hematology ProfessorSato Tsutomu Pure Neurology Associate ProfessorNakane Shunya Pure Medical Oncology/Palliative Medicine ProfessorHayashi Ryuji Pure Medical Oncology/Palliative Medicine LecturerKajiura Shinya Pure Plastic, Reconstructive and Aesthetic Surgery ProfessorSatake Toshihiko Pure Plastic, Reconstructive and Aesthetic Surgery LecturerOnoda Satoshi Pure Computational Drug Design and Mathematical Medicine ProfessorTakaoka Yutaka Pure Computational Drug Design and Mathematical Medicine Assistant ProfessorOta Mika Pure Rehabilitation Medicine ProfessorHattori Noriaki Pure Rehabilitation Medicine Assistant ProfessorOtomune Hironori Pure Biostatistics ProfessorYonemoto Naohiro Pure Behavioral Physiolog ProfessorTakao Keizo Pure Behavioral Physiolog Assistant ProfessorYasumura Misato Pure Behavioral Physiolog Assistant ProfessorFujii Kazuki Pure